<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 48

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    K103KN   E6K, V35T, E36A, T39DE, S48T, V60VI, A98S, K122E, D123E, K173A, D177DE, T200A, I202IV, Q207E, R211RK, V245Q, A272P, K277KR, T286TA, V292I, I293V, K311KR, Q334HN, G335D, R356K, M357MIT, G359T, K366KR, T377Q, K390R, A400T, E404D, V435AP, L452I, K454KR, V466I, D471E, H483Q, L491S, S519N, Q524QE, K530R, V531I, A534S, A554R V118VCFG
>16ZA.48| codons 1-560
PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKNKSVTVLDVGDAYFSGPL
DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI
YQYMDDLYVGSDLEIGQHRAKVEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEIVPLTEEAE
LELAENREILREPVHGVYYDPSKDLIAEIQKQGNDQWTYQIYQEPFKNLKTGKYAKTRTA
HTNDVRQLTEAVQKIAQESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIPGAETFYVDGAANRETKIGRAGYVTDRGRQKIVSLTETTNQKTELQ
AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEELIKKERIYLSWVPAHK
GIGGNEQVDKLVSRGIRKVL

References
Author Title Citation
Brehm, JH Frequent emergence of N348I in HIV-1 subtype C reverse transcriptase with failure of initial therapy reduces susceptibility to reverse-transcriptase inhibitors. Clin Infect Dis, 2012