Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA8371 | CA21316 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+NFV+SQV | 52 |
| 2 | 3TC+AZT+IDV | 93 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I84V, L90M | L33LI | L10I, I13V, Q18H, E35D, M36I, N37D, I62V, L63P, A71T, I72V, P79A |
| >CA21316| codons 1-99 PQITLWQRPIVTVKIGGHLKEALLDTGADDTVIEDIDLPGRWKPKIIGGIGGFIKVRQYD QVPIEICGHKTVGTVLVGATPVNVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | K20R, V35M, T39A, K43E, V90I, V111I, I135T, S162Y, E203D, H208F, R211K, A272P, K277R, T286A, E297K |
| >CA21098| codons 1-300 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALMEICAELEEEGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDIGDAYFSVPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIDELRQFLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVIPLTKEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. | J Infect Dis, 2005 |