Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6462 | CA21068 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDC | 104 |
| 2 | 3TC+AZT | 26 |
| 3 | 3TC+D4T | 204 |
| 4 | ABC+DDI+NVP | 36 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, L74V, M184V | K219Q, N348I | K103N, Y181C | T69X, K101R, K102Q, K122E, D123N, I135L, I142T, K166R, V179VI, Q207H, R211K, L228LH, A272PT, V276VI, Q278H, T286A, P345A, G359S, K366R, A371V, A376V, K390R, A400T, T403S, D460N, S468T, T470N, H483Y, L491S, K512R, S519N, V531I, K550R, A554T, K558R | K238KE |
| >CA21068| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSXRWRKVVDFRELNKRTQDFWEVQLGIPHPAGLRQNKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSLNNETPGTRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIII CQYVDDLYVGSDLEIGQHRTKIEELRHHLLKWGFTTPDQKHQKEPPFHWMGYELHPDEWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKIKHLCKLLRGAKALTEVIPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEAFKILKTGKYARMRSA HTNDVRQLTEVVQKIVTESIVIWGKTPKFRLPIQKETWETWWSEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLNDTTNQKTELQ AIYLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEQLIKKEKIYLAWVPAHK GIGGNEQVDRLVSTGIRRVL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L19IM, P39PS, I62V, L63P, V77I, I93L |
| >CA21285| codons 1-99 PQITLWQRPLVTIKIGGQIKEALLDTGADDTVLEEMNLSGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKAIGTVLIGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |