Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7108 | CA21065 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDC | 117 |
| 2 | 3TC+D4T+IDV | 52 |
| 3 | 3TC+D4T+NFV+NVP | 39 |
| 4 | Unknown | 162 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L74I, L210LW, T215F | K103N, Y181C, G190A | K238T | V8I, K43N, E44D, V111I, V118I, K122E, I135T, G196E, T200A, E203D, H208Y, R211K, H221Y, V245L, A272P, K277R, V292I, I293V, E297K |
| >CA21065| codons 1-300 PISPIETIPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELENDGKISKIGPENPYNTPV FAIKKKNSDKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDIGDAYFSIPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI CQYMDDLYVASDLEIEQHRAKIDELRQYLWKWGFFTPDKKYQKEPPFLWMGYELHPDTWT VQPILLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEIVPLTKEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, M36I, N37ND, R41K, I62IV, L63P, I64V, I93L |
| >CA21283| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYD QVPVEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. | J Infect Dis, 2005 |