<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SB-PtE SB-PtE-BL U.S. 1998 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 NRTI+SQV NA
2 NRTI+IDV+RTV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, L90M   L10I, I15V, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63H, I64M, K70R, L89M, Q92K  
>SB-PtE-BL| codons 1-99
PQITLWQRPIVTIKVEGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVKQYD
NVHMEICGHRAIGTVLVGPTPVNIIGRNMMTKIGCTLNF

References
Author Title Citation
Brun, S Patterns of protease inhibitor cross resistance in viral isolates with reduced susceptibility to lopinavir. CROI 2001, 2001
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005