<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CUPL1062 CUPL1062 Cuba 2010 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, E35D, M36I, R41K, D60E, L63P, H69Q, V77I  
>CUPL1062| codons 1-99
PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE
QIPIEICGQKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
      V179D V35T, T39A, E40D, K49R, V60I, V90I, V106I, D123E, I135K, E169D, D177E, Q197K, T200A, Q207E, R211K, Y232H, V241L, V245T, D250E, A272S, K277R, T286A, E297K, P313Q, V317A, I326V, I329V, G335D, R356K, G359S, T377Q, K390R F61L, W229C, P236T, K287G, V381M
>CUPL1062| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICADMEKEGKISRIGPENPYNTPI
LAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSITVLDVGDAYFSVPL
DKEFRKYTAFTIPSKNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPEIDI
YQYMDDLYVGSDLEIGKHRAKIEELREHLLKWGFTTPDKKHQKEPPFLCMGHELHTDKWT
LQPITLPEKESWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGAGALTEVIPLTKEAE
LELAENREILKEQVHGAYYDPSKDLVAEVQKQGQDQWTYQIYQEPFKNLKTGKYAKMRSA
HTNDVKQLTEAVQKIAQESIMIWGKTPKFRLPIQKETWEA

References
Author Title Citation
Machado, LY HIV type 1 genetic diversity in newly diagnosed Cuban patients. ARHR, 2012
Machado, LY Transmitted HIV yype 1 drug resistance in newly diagnosed Cuban patients. ARHR, 2012