<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC|AZT|IDV 52

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V     F227C V21VI, V35Q, T39D, I47M, S48T, V60I, D121Y, K122E, S162A, K173T, Q174K, D177E, T200A, E203K, Q207R, R211K K30KE
>2539.RT| codons 11-242
KLKPGMDGPKIKQWPLTEEEIKALQEICDEMEKEGKMTKIGPENPYNTPIFAIKKKDSTK
WRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLYEDFRKYTAF
TIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIVIYQYVDDLYVG
SDLEIGQHRAKIKELRRHLLKWGFTTPDKKHQKEPPCLWMGYELHPDKWTVQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V82A   T12S, I15V, L19I, M36I, N37D, K45R, L63A, H69K, L89M, I93L  
>2539.PR| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEIDLPGRWKPRMIGGIGGFIKVRQYD
QIAIEICGKKAIGTVLVGPTPANIIGRNMLTQLGCTLNF

References
Author Title Citation
El Annaz, H Drug resistance mutations in HIV type 1 isolates from patients failing antiretroviral therapy in Morocco. ARHR, 2012