<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  L33I M36MI, N37S, R41K, L63P, I93L  
>PRRT_4118| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVIEEISLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        R83K, E169D, G196K, Q207EK, R211KQ, K249KR, A272P, K277R, I293V, E297K, K311KR, E312EA, V317VA, I329L, G333E, Q334QH, R356RK, T369A, A376T, K390R, A400T, V417I, V435VI, L452A, D460N, S468F, T470N, H483HN, L517LI, S519SN  
>PRRT_4118| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPDIVI
YQYMDDLYVGSDLEIKQHRTKIEELRKHLLQWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPERDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVPLTKEAE
LELAENREILRAPVHGAYYDPSKDLIAELQKQEHGQWTYQIYQEPFKNLKTGKYAKMRGA
HTNDVKQLAEAVQKITTESIVIWGKTPKFRLPIQKETWETWWTEYWQATWIPEWEFINTP
PLVKLWYQLEKEPIIGAETFYVDGAANRETKAGKAGYVTNRGRQKVVFLNDTTNQKTELQ
AINLALQDSGLEVNIVTDSQYALGIIQAQPDKSESEIVNQIIEQLIKKEKVYLAWVPAHK
GIGGNEQVDKLVSAGIRKVL

References
Author Title Citation
Brumme, ZL HLA-associated immune escape pathways in HIV-1 subtype B gag, pol and nef proteins. PLoS Med, 2009