Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ARG-43 | ARG-43 | Argentina | 2000 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12A, I15V, M36I, N37D, R41K, R57K, Q61N, L63A |
| >ARG-43| codons 4-99 TLWQRPLVAIKVGGQLKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVKQYDNIA IEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| I135V, I142X, V179I, I202V, V245M |
| >ARG-43| codons 132-247 IPSVNNETPGXRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIIIYQYMDDLYVGS DLEIGQHRTKVEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIMLP |
References
| Author | Title | Citation |
| Kijak, GH | Resistance profiles to antiretroviral drugs in HIV-1 drug-naive patients in Argentina. | Antivir Ther, 2001 |
| Wu, TD | Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments. | J Virol, 2003 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |