<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA1449 CA20648 U.S. 2001 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 Unknown 55
2 ABC+ADV+EFV 23
3 ADV+EFV+NFV 21
4 EFV+IDV+NFV 4
5 3TC+IDV+SQV 95

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
D30N, I54V, L90M N88D I15V, E35D, M36V, N37E, R41RS, I62V, L63P, A71X W42WC
>CA20648| codons 1-99
PQITLWQRPLVTIKVGGQLKEALLDTGADNTVLEDVELPGSCKPKMIGGIGGFVKVRQYD
QVPIEICGHKXIGTVLVGPTPVNIIGRDLMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74LI, M184V, L210LW T215C     K20R, T39TA, K43KN, K122E, V179VI, R211K, A272P, T286A, I293V, T296S, E297AP  
>CA20254| codons 1-300
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICAELENEGKISKIGPENPYNTPV
FAIKKKDSTKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII
YQYVDDLYVGSDLEIGQHRTKIEELRQHLWKWGFCTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVVPLSAEAE

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005