Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA8061 | CA20588 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 130 |
| 2 | 3TC+AZT+IDV | 148 |
| 3 | D4T+DDI+EFV | 86 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A | L24I | L10I, N37D, L63P, A71V, T74TS, V77I, I93L |
| >CA20588| codons 1-99 PQITLWQRPIVTIKIGGQLKEALIDTGADDTVLEEMDLPGRWKPKLIGGIGGFVKVRQYD QIPIEICGHKVIGSVLIGPTPANIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W, T215Y | K103KN, Y188Y*FL | T39A, V106VI, D123E, I135T, S162Y, D177E, V179I, G196GE, Q207E, V241VA | Y232YH |
| >CA20198| codons 1-264 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSITVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPEIII YQYMDDLLVGSDLEIEQHRTKIEELREHLWRWGFYTPDKKHQKEPPFLWMGHELHPDKWT AQPIVLPEKDSWTVNDIQKLVGKL |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |