Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA8026 | CA20539 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ NFV | 171 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | L10V, K20I, E35D, M36I, N37S, R41K, D60E, I62V, L63P, I64V, A71V, I93L |
| >CA20539| codons 1-99 PQITLWQRPVVTIKIGGQLIEALLDTGADDTVLEDISLPGKWKPKMIGGIGGFIKVRQYE QVPVEICGHKVIGTVLVGPTPVNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215F | K219EQ | K43KQ, K46KQ, I135M, S162Y, E169D, T200A, Q207K, R211Q, V245E, A272P, R284K |
| >CA20149| codons 1-284 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEQEGQISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILDPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRAKIEELRKHLLQWGFFTPDQKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLK |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. | J Infect Dis, 2005 |