Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA8001 | CA20487 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 104 |
| 2 | 3TC+AZT | 26 |
| 3 | 3TC+AZT+IDV | 227 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47IV, V82A, L90M | L19I, K20KR, M36I, L63P, I64V, I72V, I93L |
| >CA20487| codons 1-99 PQITLWQRPLVTIKIGGQIREALLDTGADDTILEEINLPGRWKPKIVGGIGGFIKVRQYD QIPVEICGHKAVGTVLVGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, K70R, M184V, T215CF | K219Q | E6D, T200I, I202V, E203EQ, Q207D, R211K, T286A, E297A |
| >CA20098| codons 1-303 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRIKVQELRDHLLKWGFFTPDQKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVIPLTAEAE LEL |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |