Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA8000 | CA20485 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+3TC+IDV | 52 |
| 2 | 3TC+D4T+NFV | 13 |
| 3 | 3TC+D4T+NVP | 150 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46ML | L10I, K20R, N37D, D60E, L63X, I64V, V77I, I85V, I93L |
| >CA20485| codons 1-99 PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEEMDLPGRWKPKLIGGIGGFIKVRQYE QIXVEICGHKAIGTVLIGPTPVNIVGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | A62V | Y181C | D121DH, D123E, I135R, K166R, D177E, Q197QK, R211G, F214L, H221HY, L228LR, V245E, E248Q, A272P, T286A, I293V |
| >CA20096| codons 1-298 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HKEFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPEIVI CQYVDDLYVGSDLEIGKHRTKIEELRQHLLGWGLTTPDKKYQKEPPFRWMGYELHPDKWT VQPIELPQKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVVPLTEE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |