Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7983 | CA20446 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+DDI+IDV | 222 |
| 2 | 3TC+D4T+NFV+NVP | 13 |
| 3 | 3TC+DDI+IDV | 6 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I84V, L90M | G73S | L10I, I13V, K14R, I15V, N37D, K45R, Q61E, I62V, L63P, I66L, A71T, I72R, V77I, I93L |
| >CA20446| codons 1-99 PQITLWQRPIVTVRVGGQLKEALLDTGADDTVLEEMDLPGRWKPRMIGGIGGFIKVRQYD EVPIELCGHKTRSTVLIGPTPVNVIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V106A | F227L | K122E, D123N, I135T, I178IM, G196E, T200I, V245VL, T286A | Q258QH, N265ND |
| >CA20070| codons 1-286 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSATVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMVI YQYMDDLYVGSDLEIEQHRIKIEELRQHLLRWGFTTPDKKHQKEPPLLWMGYELHPDKWT VQPILLPEKDSWTVNDIHKLVGKLDWASQIYAGIKVKQLCKLLRGA |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. | J Infect Dis, 2005 |