Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7909 | CA20361 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDC | 52 |
| 2 | 3TC+D4T | 122 |
| 3 | 3TC+D4T+IDV | 43 |
| 4 | 3TC+D4T+NFV | 48 |
| 5 | 3TC+D4T+NFV+SQV | 118 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82T | L24I, K43T, F53L | L10I, K20R, E35D, M36I, N37E, L63P, I64V, T74K |
| >CA20361| codons 1-99 PQITLWQRPIVTIKIGGQLREALIDTGADDTVLEDIELPGRWTPKIIGGIGGLVKVRQYD QIPVEICGHKAIGKVLVGPTPTNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215Y | K20R, K43E, E44A, V60I, V118I, K122E, G196E, T200A, E203D, H208Y, R211D, T286A, I293V |
| >CA19968| codons 1-300 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEEAGKISKIGPENPYNTPI FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIEQHRAKIDELRQYLWDWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVPLTEEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |