Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1626 | CA20334 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 91 |
| 2 | DDI | 17 |
| 3 | AZT | 21 |
| 4 | 3TC+AZT | 30 |
| 5 | 3TC+AZT+SQV | 30 |
| 6 | 3TC+AZT+IDV | 105 |
| 7 | 3TC+AZT+IDV | 17 |
| 8 | Unknown | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, I84IV | L10I, M36MI, N37NS, L63T, H69Q, A71AV, I93IL |
| >CA20334| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEISLPGRWKPKIIGGIGGFIKVRQYD QITIEICGQKVIGTVLVGPTPVNVIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | K219Q | K20R, V35T, V60I, V106I, D123E, I135IV, S162C, K166R, D177DE, I178L, Q197E, F214L, D218E, A272P, K277R, I293V, E297K |
| >CA19941| codons 1-303 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAYFSVPL DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTRILEPFRKQNPELVI YQYVDDLYVGSDLEIGEHRTKIEELRQHLLRWGLTTPEQKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVPLTKEAE LEL |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |