Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1342 | CA20303 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 8 |
| 2 | None | 9 |
| 3 | AZT | 34 |
| 4 | AZT+DDC | 22 |
| 5 | D4T+NFV | 15 |
| 6 | 3TC+DDI+NFV | 4 |
| 7 | 3TC+AZT+NFV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90M | L10V, K20M, M36I, K43KN, L63P, H69Q, A71T |
| >CA20303| codons 1-99 PQITLWQRPVVTIKIGGQLMEALLDTGADDTVLEEINLPGRWNPKIIGGIGGFIKVRQYD QIPIEICGQKTIGTVLVGPTPVNIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215F | T39A, K122E, S134SR, I142V, K154KE, A158AS, D177DE, D218DE, A272P, V292VI, I293V |
| >CA19910| codons 1-295 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPRINNETPGVRYQYNVLPQGWEGSPSIFQSSMTKILEPFRKQNPEIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFFTPEKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEIVPL |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |