<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA1342 CA20303 U.S. 2000 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 8
2 None 9
3 AZT 34
4 AZT+DDC 22
5 D4T+NFV 15
6 3TC+DDI+NFV 4
7 3TC+AZT+NFV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, L90M   L10V, K20M, M36I, K43KN, L63P, H69Q, A71T  
>CA20303| codons 1-99
PQITLWQRPVVTIKIGGQLMEALLDTGADDTVLEEINLPGRWNPKIIGGIGGFIKVRQYD
QIPIEICGQKTIGTVLVGPTPVNIIGRNLMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, T215F       T39A, K122E, S134SR, I142V, K154KE, A158AS, D177DE, D218DE, A272P, V292VI, I293V  
>CA19910| codons 1-295
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPRINNETPGVRYQYNVLPQGWEGSPSIFQSSMTKILEPFRKQNPEIVI
YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFFTPEKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEIVPL

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005