Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7861 | CA20290 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV+ 3TC+ AZT | 26 |
| 2 | DDI+ IDV+ 3TC | 13 |
| 3 | 3TC+ D4T+ SQV+ RTV | 34 |
| 4 | 3TC+ AZT+ EFV | 17 |
| 5 | 3TC+ D4T+ RTV | 47 |
| 6 | Unknown | 67 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47V, V82A | K43KQ, L63P, I64L, I93L |
| >CA20290| codons 16-99 GGQLKEALLDTGADDTILEEMNLPGRWQPKIVGGIGGFIKVRQYDQIPLEICGHKAIGTV LVGPTPANIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V, M184V | D177E, I178M, V179VG, T200A, Q207E, V245E | Q145QP |
| >CA19898| codons 1-257 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYPYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMGI YQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDI |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |