Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5199 | CA20287 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 8 |
| 2 | AZT+DDI | 21 |
| 3 | 3TC+AZT+IDV | 228 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A, L90M | Q58E, T74TP | L10I, L19Q, L63P, H69R, I93L, C95F |
| >CA20287| codons 1-99 PQITLWQRPIVTIKIGGQQKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFVKVREYD QIPIEICGRKAIGPVLVGPTPANIIGRNLMTQLGFTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215Y | K22KN, V35M, T39A, K122E, T200TI, V245E, A288S, T296TS, E297A, E300R | K281KE, I293GV |
| >CA19896| codons 1-300 PISPIETVPVKLKPGMDGPKVNQWPLTEEKIKALMEICAEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRIKIEELRQHLLRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCELLRGTKSLTEVGPLSAEAR |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive value of HIV-1 genotypic resistance test interpretation algorithms. | J Infect Dis, 2009 |