Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7859 | CA20286 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 83 |
| 2 | 3TC+AZT | 35 |
| 3 | 3TC+AZT+NFV | 96 |
| 4 | D4T+IDV+NVP | 17 |
| 5 | ABC+APV+DDI | 71 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54M, I84V, L90M | L33F | L10I, I13V, K20T, L63P, A71V, T74S, V77I, I93L |
| >CA20286| codons 1-99 PQITLWQRPIVTVKIGGQLTEALLDTGADDTVFEEMNLPGRWKPKIIGGIGGFMKVRQYD QIPIEICGHKVIGSVLIGPTPVNVIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, M184V, L210W, T215Y | Y188L | T69N, D121CY, K122E, I135V, I142V, S162C, V179I, T200I, I202V, Q207QH, V245VL, A272P, K277R, L283I, K287KQ, A288T, I293V |
| >CA19895| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKDSNKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL CEDFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIII YQYVDDLLVGSDLEIGQHRIKVEELRHHLWRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPILLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIRGTQTLTEVVPLTEEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |