Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4414 | CA20174 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 12 |
| 2 | AZT+ 3TC | 9 |
| 3 | DDI+ D4T+ NVP | 24 |
| 4 | D4T+ NVP | 43 |
| 5 | D4T+ EFV+ SQV | 12 |
| 6 | D4T+ EFV+ SQV | 25 |
| 7 | D4T+ 3TC+ ABC+ NFV+ APV | 13 |
| 8 | Unknown | 62 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103KN, Y181YC | T27S, K49R, V60VI, R83RK, V90I, K102KR, D123E, I135V, D177E, G196GE, R211K |
| >CA20174| codons 1-256 PISPIETVPVKLKPGMDGPKVKQWPLSEEKIKALVEICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKKTQDFWEIQLGIPHPAGLKRNKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI CQYMDDLYVGSDLEIEQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVND |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, E35ED, N37D, D60DE, L63S |
| >CA20563| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEDMDLPGRWKPKMIGGIGGFIKVRQYE QISIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |