<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA8000 CA20096 U.S. 2000 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 D4T+3TC+IDV 52
2 3TC+D4T+NFV 13
3 3TC+D4T+NVP 150

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V A62V Y181C   D121DH, D123E, I135R, K166R, D177E, Q197QK, R211G, F214L, H221HY, L228LR, V245E, E248Q, A272P, T286A, I293V  
>CA20096| codons 1-298
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
HKEFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPEIVI
CQYVDDLYVGSDLEIGKHRTKIEELRQHLLGWGLTTPDKKYQKEPPFRWMGYELHPDKWT
VQPIELPQKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVVPLTEE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46ML   L10I, K20R, N37D, D60E, L63X, I64V, V77I, I85V, I93L  
>CA20485| codons 1-99
PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEEMDLPGRWKPKLIGGIGGFIKVRQYE
QIXVEICGHKAIGTVLIGPTPVNIVGRNLLTQLGCTLNF

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005