Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7995 | CA20085 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 157 |
| 2 | 3TC+D4T+NVP | 188 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, D67N, T69D, L74LV, M184V, L210W, T215Y | Y181GV | K43KE, R83K, A98S, K101Q, G196E, T200I, E203X, Q207DN, R211K, H221HY, L228LH, K249Q, D250E | A299AG |
| >CA20085| codons 1-303 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEEGKISKIGPENPYNTPV FAIKKKNSDKWRKVVDFRELNKKTQDFWEVQLGIPHPSGLQKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI GQYVDDLYVGSDLEIEQHRIKIXELRDHLWKWGFYTPDKKYQKEPPFHWMGYELHPDKWT VQPIVLPEQESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVIPLTEEGE LEL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L33IV | N37X, L63X, I64V, I72IT |
| >CA20451| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVIEEMXLPGRWKPKMIGGIGGFIKVRQYD QIXVEICGHKATGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |