<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP 52

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N A98G V35T, E40D, V60I, I135L, S162A, K166R, K173T, Q174R, D177E, G196E, T200A, Q207E, R211K, V245Q, K275Q, K277R, T286A, E291D, V292I, I293V, P294T, L295M, S322T, I326V, R356K, M357R, G359S, T369I, A371V, I375A, T377V, K390R, T403M, E415EK, E432D, V435A  
>08TG.E5068| codons 1-443
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKNKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQASMTRILEPFRTRNPEIVI
YQYVDDLYVGSDLEIEQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIQVRQLCKLLRGAKALTDIVTMTEEAE
LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQGQWTYQIYQEPFKNLKTGKYAKRRSA
HTNDVKQLIEVVQKAAVESIVIWGKTPKFRLPIQKETWEAWWMEYWQATWIPEWKFVNTP
PLVKLWYQLEKDPIAGAETFYVD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I13V, I15L, K20I, M36I, R41K, L63T, I64M, H69K, K70R, L89M  
>08TG.E5068| codons 1-99
PQITLWQRPLVSVKLGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QITMEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Dagnra, AY High prevalence of HIV-1 drug resistance among patients on first-line antiretroviral treatment in Lome, Togo. J Int AIDS Soc, 2011