<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP 52

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   Y181V   V35T, K49KR, A98S, K102R, G112GE, D121H, K122E, I135V, A158T, S162A, K173A, Q174K, D177E, I178M, V189I, T200A, Q207A, R211E, V245Q, A272P, Q278N, K281R, T286A, E291D, V292I, I293V, E297A, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, T377M, K388KR, K390R, A400T, T403M, E432D, V435I I31IK, L246LR, W414W*
>08TG.E5043| codons 1-435
PISPIETVPVKLKPGMDGPKVKQWPLTEEKKKALTEICTEMEKEGKISRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKRKKSVTVLDVEDAYFSVPL
HEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPTIFQASMTKILEPFRAKNPEMVI
VQYVDDLYIGSDLEIGQHRAKIEELRAHLLEWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQRPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKNLCRLLRGAKALTDIVPLTAEAE
LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA
HTNDVKQLTEVVQKVAMESIVIWGKTPRFRLPIQKETWETWWMEYWQATWIPE*EFVNTP
PLVKLWYQLEKDPII

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, Q18R, K20I, E35D, M36I, N37S, R41K, H69K, L89M  
>08TG.E5043| codons 1-99
PQITLWQRPLVTVRIGGRLIEALLDTGADDTVLEDISLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Dagnra, AY High prevalence of HIV-1 drug resistance among patients on first-line antiretroviral treatment in Lome, Togo. J Int AIDS Soc, 2011