<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP 52

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R   K103N, Y181C   V8I, V35K, V60I, S68G, I135V, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357R, G359S, T369A, A371V, I375V, A376T, T386A, K390R, K395R, E396D, A400T, T403M, E432D, V435A  
>08TG.E5025| codons 1-443
PISPIETIPVKLKPGMDGPKVKQWPLTEEKIKALKEICTEMEKEGKISKIGPENPYNTPI
FAIKRKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAKNPEIVI
CQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRRSA
HTNDVKQLAEVVQKVTTESIVIWGKAPKFRLPIQRDTWETWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIAGAETFYVD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, M36I, N37S, R41K, I64L, H69K, K70R, L89M  
>08TG.E5025| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYD
QILLEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Dagnra, AY High prevalence of HIV-1 drug resistance among patients on first-line antiretroviral treatment in Lome, Togo. J Int AIDS Soc, 2011