<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP 52

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, D67N   V106M, Y188C   V35T, V60I, D123E, I135V, T139S, S162A, K173T, Q174K, D177E, Q197E, T200A, E204Q, Q207E, R211K, F214L, V245Q, E248D, V276I, L283I, T286A, E291D, I293V, E297Q, S322T, I326V, Q334D, G335D, R356K, M357R, G359S, A371V, I375V, T377M, K390R, T403M, E404D, E432D, V435I I31IK
>08TG.E5009| codons 1-436
PISPIETVPVKLKPGMDGPKVKQWPLTEEKKKALTEICTEMEKEGKISKIGPENPYNTPI
FAIKRKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL
DKEFRKYTAFTIPSVNNESPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIVI
YQYMDDLCVGSDLEIGEHRAKIEQLREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYAGIKIKQLCKLIRGAKALTDVVPLTQEAE
LELAENREILKEPVHGVYYDPTKDLVAEIQKQGDDQWTYQIYQEPFKNLKTGKYAKRRSA
HTNDVKQLTEVVQKVAMESIVIWGKTPKFRLPIQKETWEAWWMDYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIIG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, G16E, K20I, P39Q, R41K, H69K, K70R, I72V, L89M, Q92QR, T96TP M36K
>08TG.E5009| codons 1-99
PQITLWQRPLVTVKIEGQLIEALLDTGADDTVLEEKNLQGKWKPKMIGGIGGFIKVRQYD
QILIEICGKRAVGTVLVGPTPVNIIGRNMLTRIGCPLNF

References
Author Title Citation
Dagnra, AY High prevalence of HIV-1 drug resistance among patients on first-line antiretroviral treatment in Lome, Togo. J Int AIDS Soc, 2011