<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP 52

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    Y181C   V35VA, E36D, K64KN, S162A, K173T, Q174N, T200A, Q207E, R211K, H221HY, V245Q, A272P, Q278N, T286A, E291D, V292I, I293V, E297A, S322T, D324E, G335D, R356K, M357R, G359S, A371V, T377LV, K390R, T403L, E432D, V435I  
>08TG.T3047| codons 1-446
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALADICTEMEKEGKISKIGPENPYNTPV
FAINKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTNNPDIVI
CQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKYQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKNLCKLLRGAKALTDIVPLTAEAE
LELAENREILKEPVHGVYYDPTKELIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRRSA
HTNDVKQLTEVVQKIAVESIVIWGKTPKFRLPIQKETWEAWWLEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIIGAETFYVDGAA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13AV, K20I, M36I, N37S, R41K, H69K, L89M  
>08TG.T3047| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Dagnra, AY High prevalence of HIV-1 drug resistance among patients on first-line antiretroviral treatment in Lome, Togo. J Int AIDS Soc, 2011