<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP 52

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70R, M184V, T215F D67G, K219E Y181C V108I K20R, V35T, K64H, L109I, K122E, D123N, I135T, S162A, E169Q, K173T, Q174K, N175Y, D177E, T200A, I202V, Q207E, R211K, F214L, H221Y, L228H, V245E, E248D, D250E, L283I, T286A, E291D, V292I, I293V, P294T, S322T, D324E, I326V, G335D, R356K, M357R, G359S, A371V, I375V, A376T, T377I, K390R, A400T, T403M  
>08TG.T3046| codons 1-429
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV
FAIHKKGSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTIIDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILQPFRTKYPEIVI
CQYVDDLYVGSDLEIGQHRAKVEELREHLLKWGLFTPDEKYQKEPPFHWMGYELHPDKWT
VQPIELPDKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLIRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPTKELVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRRSA
HTNDVKQLTEVVQKVTIESIVIWGKTPKFRLPIQKETWETWWMEYWQATWIPEWEFVNTP
PLVKLWYQL

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, G16E, K20I, M36L, R41K, L63S, I64L, H69K, L89M  
>08TG.T3046| codons 1-99
PQITLWQRPLVTVRIEGQLIEALLDTGADDTVLEELNLPGKWKPKMIGGIGGFIKVRQYD
QISLEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Dagnra, AY High prevalence of HIV-1 drug resistance among patients on first-line antiretroviral treatment in Lome, Togo. J Int AIDS Soc, 2011