<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP 52

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, M184V, T215TNSY V75VM, N348I Y181C   V35T, K49R, I50V, V60I, I135R, A158AS, K173T, Q174K, N175NY, D177E, T200E, Q207G, R211K, V245N, K281R, T286A, E291D, I293V, P294T, P313S, S322T, G335D, R356K, M357R, G359S, A371V, I375A, T377I, K390R, A400T, T403M, E404D, E432D Y56YF, S162ADE
>08TG.T3003| codons 1-433
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKEGKISRVGPENPFNTPI
FAIKKKDSTKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPSIFQESMTKILEPFRTKYPEIVI
CQYVDDLYVGSDLEIGQHREKIEELRGHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPINLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDVVTLTEEAE
LELAENREILKESVHGVYYDPTKDLIAEIQKQGQDQWTYQIYQEPFKILKTGKYAKRRSA
HTNDVKQLTEVVQKAAIESIVIWGKTPKFRLPIQKETWETWWMDYWQATWIPEWEFVNTP
PLVKLWYQLEKDP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, G16E, K20I, M36I, R41K, H69K, L89M  
>08TG.T3003| codons 1-99
PQITLWQRPLVTVRIEGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Dagnra, AY High prevalence of HIV-1 drug resistance among patients on first-line antiretroviral treatment in Lome, Togo. J Int AIDS Soc, 2011