<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT 157

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, M184V, L210W, T215Y N348I     E28EK, K32KEQ, K43Q, E44D, V118I, D121HY, K122E, I135T, G196GE, T200I, E203K, Q207E, H208Y, R211K, L228H, A272P, A288AT, E297EK, I326IT, P345PQ, R356K, A360V, T377L, S379CG, K390KR  
>14439342| codons 1-400
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIQALVEICTELEQDGKISKIGPENPYNTPV
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIEQHRIKIKELREYLWKWGFYTPDKKHQKEPPFHWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKTLTEVIPLTKEAE
LELAENREILKEPVHGVYYDPSKDLTAEIQKQGQGQWTYQIYQEQFKILKTGKYAKMRGV
HTNDVKQLTEAVQKIALEGIVIWGKTPKFRLPIQKETWEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  L10F T12S, K14R, I15V, P39S, R41K, D60E, L63P, I64V  
>14439342| codons 1-99
PQITLWQRPFVSIRVGGQLKEALLDTGADDTVLEEMNLSGKWKPKMIGGIGGFIKVRQYE
QIPVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
von Wyl, V HIV-1 reverse transcriptase connection domain mutations: dynamics of emergence and implications for success of combination antiretroviral therapy. Clin Infect Dis, 2010