<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 AZT 65
2 3TC+AZT 56

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    Q7E, I13V, K14R, I15V, L19I, M36I, R41K, I62V, L63P, I72V, V77I  
>4796734| codons 1-99
PQITLWERPLVTVRVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QVPIEICGHKAVGTVLIGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, M184V, L210W, T215Y K219E     V35T, V60I, K101R, K122E, D123N, I135T, K166R, D177E, E203K, Q207E, R211K, V245K, D250E, A272P, Q334D, Y342F, M357A, T369A, S379G, K385R, K390R, K395R  
>4796734| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKEGKISKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLRKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPEIVI
YQYVDDLYVGSDLEIGQHRTKIKELREHLWKWGFYTPDEKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGDGQWTYQIFQEPFKNLKTGKYARARGA
HTNDVKQLAEAVQKIATEGIVIWGRTPKFRLPIQRETWE

References
Author Title Citation
von Wyl, V HIV-1 reverse transcriptase connection domain mutations: dynamics of emergence and implications for success of combination antiretroviral therapy. Clin Infect Dis, 2010