<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+ABC+AZT 251

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, M184V, L210W, T215Y N348I     K43E, E44ED, V60I, V118VI, D123E, D177DE, Q207E, R211K, K249Q, A272P, Q278HN, K281R, T286A, I293V, E297K, K311R, S322T, Q334L, M357T, G359GS, K385R, K390R, E399K  
>1506769| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEDGKISKIGPENPYNTPI
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI
YQYVDDLYVGSDLEIGQHRTKIEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEQDSWTVNDIQKLVGKLNWASQIYPGIKVKNLCRLLRGAKALTEVVPLTKEAE
LELAENREILREPVHGVYYDPTKDLIAEIQKQGLGQWTYQIYQEPFKILKTGKYARTRSA
HTNDVKQLTEAVQKIATESIVIWGRTPKFRLPIQKETWK

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I3IN, L5LF, A22AV, K43R, L63LP, H69K, A71T, V77I, I93LV  
>1506769| codons 1-99
PQNTFWQRPLVTIKIGGQLKEVLLDTGADDTVLEEMNLPGRWRPKMIGGIGGFIKVRQYD
QIPIEICGKKTIGTVLIGPTPVNIIGRNLLTQVGCTLNF

References
Author Title Citation
von Wyl, V HIV-1 reverse transcriptase connection domain mutations: dynamics of emergence and implications for success of combination antiretroviral therapy. Clin Infect Dis, 2010