<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP 257

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N, Y181C   K20KR, V35T, T39E, K49KR, K122E, D123S, I142IV, Q145H, K173A, Q174K, V179I, T200A, Q207E, F214FL, H221Y, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
>70101829| codons 1-319
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEEMEKEGKISRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGVRYHYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPDIII
CQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGLTTPDKKYQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYY

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L   T12S, I15V, L19I, R41K, D60E, L63P, H69K, V77I, L89M, I93L  
>70101829| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEMNLPGKWKPKLIGGIGGFIKVRQYE
QIPIEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Luebbert, J Virological failure and drug resistance in patients on antiretroviral therapy after treatment interruption in Lilongwe, Malawi. Clin Infect Dis, 2012