<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN, M184V, T215F   K101E, Y181C, G190A   K20R, V35T, T39D, K122E, D123E, E138Q, I142V, E169ED, K173A, Q174K, D177E, I178IL, Q207E, V241VI, P243A, V245Q, E248D, K249KE, A272P, K275R, Q278H, T286A, E291D, I293V, P294T, E297A, L303LM, Q334H, G335D, F346H  
>CIRCB-11096| codons 1-352
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICDEMEKEGKISKIGPENPYNTPV
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL
DEEFRKYTAFTIPSINNQTPGVRYQYNVLPQGWKGSPAIFQSSMTKILDPFRAKNPELVI
CQYVDDLYVASDLEIGQHRTKIEELREHLLRWGFFTPDKKHQKEPPFLWMGYELHPDKWT
IQAIQLPDEDSWTVNDIQKLVGKLNWASQIYPGIRVKHLCKLLRGAKALTDVVTLTAEAE
LEMAENREILKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPHKNLKTG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I15V, K20R, M36I, R41K, I62V, L63T, E65ED, H69Q  
>CIRCB-11096| codons 1-99
PQITLWQRPVVTIKVGGQLREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QVTIDICGQKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Fokam, J Drug resistance among drug-naive and first-line antiretroviral treatment-failing children in Cameroon. Pediatr Infect Dis J, 2011