<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, M184V, L210W, T215Y       V35T, E44D, V60I, K64KR, D121H, K122E, I135T, S162DN, S163A, Q174K, D177E, G196E, T200A, E203K, E204D, Q207D, H208Y, R211K, H221Y, V245M, A272P, E291D, I293V, E298EG, E308K N137NY, Q145QP, Q182Q*, D237DA
>CIRCB-10615| codons 1-314
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKDGKISKIGPENPYNTPI
FAIRKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
HEDFRKYTAFTIPSTNYETPGIRYPYNVLPQGWKGSPAIFQNAMTKILEPFRKKNPEIVI
Y*YVDDLYVGSDLEIEQHRAKIKDLRDYLWKWGFYTPDKKYQKEPPFLWMGYELHPAKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDVVPLTEGAE
LELAENRKILKEPV

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  M46MV, I47IM T12TP, I13V, K14R, I15V, Q18E, K20KR, E35D, M36I, N37DE, R41RK, H69K, L89M D25DG
>CIRCB-10615| codons 7-99
QRPLVPVRVGGELREALLGTGADDTVLEDIELPGKWKPKVMGGIGGFIKVRQYDQILIEI
CGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Fokam, J Drug resistance among drug-naive and first-line antiretroviral treatment-failing children in Cameroon. Pediatr Infect Dis J, 2011