<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N A98G, V108I V35T, T39A, V90I, K122KE, D123T, I135V, S162A, K173T, Q174K, D177E, T200A, Q207N, R211K, V245Q, E248D, K275Q, V276I, T286A, E291D, V292VI, I293V, P294T, E300K, S322T  
>CIRCB-10124| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPGGLKKNKSVTILDVGDAYFSVPL
DETFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELRNHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYAGIQIKQLCKLLRGAKALTDIVTLTEEAK
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10LV, T12A, I13V, I15V, K20I, E35D, M36I, R41K, K43R, Q61H, L63P, G68E, H69R, K70R, L89M  
>CIRCB-10124| codons 1-99
PQITLWQRPVVAVKVGGQLIEALLDTGADDTVLEDINLPGKWRPKMIGGIGGFIKVRQYD
HIPIEICERRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Fokam, J Drug resistance among drug-naive and first-line antiretroviral treatment-failing children in Cameroon. Pediatr Infect Dis J, 2011