<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, T69DN, M184V, T215Y   K103N, Y181C   P4PS, K20KR, V35T, K43KE, V60I, K102Q, I135V, I142IV, S162A, K173T, Q174K, D177E, T200A, E203EK, Q207A, R211K, H221HY, K223KE, L228LR, V245Q, T286A, A288T, E291D, V292I, I293V, P294T, L295M, S322A, G335GD  
>CIRCB-7815| codons 1-341
PISSIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTELEEEGKISKIGPENPYNTPI
FAIKKKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQNKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIVI
CQYVDDLYVGSDLEIGQHRAKIKELRAHLLKWGFYTPDKKYQEEPPFRWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKTLTDIVTMTEEAE
LELAENREILKEPVHGVYYDPAKDLIAEIQKQGQDQWTYQI

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14KR, G16GE, K20I, E35D, M36I, R41K, K43KR, H69K, K70KR, L89M, I93IM  
>CIRCB-7815| codons 1-99
PQITLWQRPLVTVRIEGQLIEALLDTGADDTVLEDINLPGKWRPKMIGGIGGFIKVRQYD
QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQMGCTLNF

References
Author Title Citation
Fokam, J Drug resistance among drug-naive and first-line antiretroviral treatment-failing children in Cameroon. Pediatr Infect Dis J, 2011