Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, T69DN, M184V, T215Y | K103N, Y181C | P4PS, K20KR, V35T, K43KE, V60I, K102Q, I135V, I142IV, S162A, K173T, Q174K, D177E, T200A, E203EK, Q207A, R211K, H221HY, K223KE, L228LR, V245Q, T286A, A288T, E291D, V292I, I293V, P294T, L295M, S322A, G335GD |
| >CIRCB-7815| codons 1-341 PISSIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTELEEEGKISKIGPENPYNTPI FAIKKKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIVI CQYVDDLYVGSDLEIGQHRAKIKELRAHLLKWGFYTPDKKYQEEPPFRWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKTLTDIVTMTEEAE LELAENREILKEPVHGVYYDPAKDLIAEIQKQGQDQWTYQI |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14KR, G16GE, K20I, E35D, M36I, R41K, K43KR, H69K, K70KR, L89M, I93IM |
| >CIRCB-7815| codons 1-99 PQITLWQRPLVTVRIEGQLIEALLDTGADDTVLEDINLPGKWRPKMIGGIGGFIKVRQYD QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQMGCTLNF |
References
| Author | Title | Citation |
| Fokam, J | Drug resistance among drug-naive and first-line antiretroviral treatment-failing children in Cameroon. | Pediatr Infect Dis J, 2011 |