Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20R, M36I, N37D, R41K, H69K, K70R, L89I, N98K |
| >CIRCB-3241| codons 1-99 PQITLWQRPLVTVRIGGQLREALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKRAIGTVLVGPTPVNIIGRNILTQIGCTLKF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | Y181C | A98G, K101H | I5M, E6K, P9Q, V10I, V35R, E36R, T39L, D123E, T139R, S162G, Q174E, D177E, T200A, Q207E, F214L, V245Q, T286A, E291D, V292I, I293V, A304E, S322T, I326V, G335D | T7R, V8P, M16R |
| >CIRCB-3241| codons 1-356 PISPMKRPQIKLKPGRDGPKVKQWPLTEEKIKALRRICLEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLHKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNERPGIRYQYNVLPQGWKGSPAIFQGSMTKILEPFRKENPEIVI CQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVPLTEEAE LELEENREILKEPVHGVYYDPTKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAR |
References
| Author | Title | Citation |
| Fokam, J | Drug resistance among drug-naive and first-line antiretroviral treatment-failing children in Cameroon. | Pediatr Infect Dis J, 2011 |