<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V   K103N V108I K20R, V35T, E40D, K43KR, V60I, K104R, D121H, K122E, E169D, Q174E, D177E, T200A, E203K, Q207A, R211K, K223T, V241M, V245Q, E248D, D250E, S251N, A272P, K277R, Q278H, T286A, E291D, I293V, E297A, L301M, K311R  
>CIRCB-3194| codons 1-316
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTDLEREGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNRSVTILDVGDAYFSVPL
HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKENPEIVI
YQYVDDLYVGSDLEIGQHRAKIKELRAHLLKWGFTTPDKKHQTEPPFLWMGYELHPDKWT
MQPIQLPDKENWTVNDIQKLVGKLNWASQIYPGIKVRHLCKLLRGAKALTDVVPLTAEAE
MELAENREILREPVHG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, L90M   I13V, K14R, G17E, K20I, E35D, M36V, R41K, I62V, I64V, C67S, H69K, V82I, L89M  
>CIRCB-3194| codons 1-99
PQITLWQRPLVTVRIGEQLIEALLDTGADDTVLEDVNLPGKWKPKIIGGIGGFIKVRQYD
QVLVEISGKKAIGTVLVGPTPINIIGRNMMTQIGCTLNF

References
Author Title Citation
Fokam, J Drug resistance among drug-naive and first-line antiretroviral treatment-failing children in Cameroon. Pediatr Infect Dis J, 2011