<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V V75M, T215TS K103N   E6K, T7P, P9A, K11Q, V21VI, V35T, K49R, V90I, K122E, D123N, I135T, E138EG, S162N, R172K, D177E, I178L, V179IT, T200A, E204K, Q207E, R211K, F214L, D237E, V245K, D250E, A272P, V276VI, K281KR, L283LI, T286A, E297K, K311R, D324DE, Q334E, G335S, T338S, Y339W, R356K, R358K, G359S, A371T Q182S
>CIRCB-1519| codons 1-372
PISPIKPVAVQLKPGMDGPKIKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPV
FAIKKKDSTKWRKLMDFRELNKRTQDFWEIQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNGTPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFKKQNPELTI
YSYVDDLYVGSDLEIGQHRAKIEKLREHLLKWGLSTPDKKHQKEPPFLWMGYELHPEKWT
VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIKIKQLCRLIRGAKALTEVIPLTKEAE
LELAENREILREPVHGVYYDPSKELIAEIQKQGESQWSWQIYQEPFKNLKTGKYAKMKSA
HTNDVKQLTETV

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, E35D, M36I, R41K, L63P, H69Q  
>CIRCB-1519| codons 1-99
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGQKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Fokam, J Drug resistance among drug-naive and first-line antiretroviral treatment-failing children in Cameroon. Pediatr Infect Dis J, 2011