<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
J0747 J0747-1 Uganda 2007 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, T215TFIS   G190A, M230ML   P14PL, V35T, E40D, K49R, F87FL, V90I, K122E, D123N, I135T, S162SN, K173S, V179I, T200A, Q207A, R211S, V245Q, E291D, P294T K64KE, H96HR
>J0747-1| codons 1-305
PISPIETVPVKLKLGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKISRIGPENPYNTPV
FAIEKKDSTKWRKLVDFRELNKRTQDLWEIQLGIPRPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRSQNPDIII
YQYVDDLYVASDLEIGQHRAKIEELRAHLLSWGFSTPDKKHQKEPPFLWLGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTDVITLTEEAE
LELAE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13IV, K14KR, I15V, E35D, M36I, R41K, H69K, L89M, C95CR  
>J0747-1| codons 1-99
PQITLWQRPLVTVRVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGRTLNF

References
Author Title Citation
Reynolds, SJ Antiretroviral drug susceptibility among HIV-infected adults failing antiretroviral therapy in Rakai, Uganda. ARHR, 2012