<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   Y188L   E6ED, K11KT, K20R, V21I, V35T, E40D, K49R, I50V, V60I, K122E, D123N, T165TI, K173S, D177E, V179I, T200A, I202V, Q207A, V245E, T286A, I293V, P294T  
>E7105-1| codons 1-305
PISPIDTVPVTLKPGMDGPRIKQWPLTEEKIKALTEICTDMEKEGKISRVGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRSQNPEIII
YQYVDDLLVGSDLEIGQHRAKVEELRAHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVTLTEEAE
LELAE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, K14KN, G16E, K20R, E35D, M36I, R41K, K45R, R57K, L63Q, I64IM, H69K, K70R, L89M P81PS
>E7105-1| codons 1-99
PQITLWQRPVVTVNIEGQLREALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYD
QIQMEICGKRAIGTVLVGPTSVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Reynolds, SJ Antiretroviral drug susceptibility among HIV-infected adults failing antiretroviral therapy in Rakai, Uganda. ARHR, 2012