Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7877 | CA19917 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 31 |
| 2 | 3TC+AZT | 17 |
| 3 | 3TC+AZT+IDV | 109 |
| 4 | D4T+DDI+NFV | 121 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, T215F | K219Q | E6D, T39TA, V60I, K103R, V118I, K122E, F124FL, I142IM, Q197K, T200E, E203D, Q207D, F214L, K223Q, L228LH, Q242K, V245M, A272P, V276T, L283I, A288T, I293V, E297A | T131TRS |
| >CA19917| codons 1-300 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSIPL DEDLRKYTAFSIPSINNETPGMRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGKHREKIDELRDHLLRWGLFTPDQKHQQEPPFHWMGYELHPDKWT VKPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKTKQLCKLIRGTKTLTEVVPLTAEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82F, L90M | L10I, I15V, L19I, R57K, L63A, I66L, A71V, I93L |
| >CA20311| codons 1-99 PQITLWQRPIVTIKVGGQIKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFVKVKQYD QIAIELCGHKVIGTVLVGPTPFNIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | Genotypic predictors of human immunodeficiency virus type 1 drug resistance. | PNAS, 2006 |
| Melikian, GL | Standardized comparison of the relative impacts of HIV-1 reverse transcriptase (RT) mutations on nucleoside RT inhibitor susceptibility. | AAC, 2012 |