Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5617 | CA19872 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 70 |
| 2 | 3TC+AZT+IDV | 105 |
| 3 | 3TC+D4T+IDV | 118 |
| 4 | APV+D4T+EFV | 21 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W, T215Y | K101KE, G190S | E6K, K43N, V118I, K122E, I135V, V179I, V189VI, Q197QH, T200A, E203D, R211KT, L228H | D17DA, I180IM, Y232YS, L260LF |
| >CA19872| codons 1-260 PISPIKTVPVKLKPGMAGPKVKQWPLTEEKIKALVEICTELENEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIIM YQYMDDLYISSDLEIGHHRAKIDELRQHLWTWGFYTPDKKHQKEPPFHWMGSELHPDKWT VQPIVLPEKDSWTVNDIQKF |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L76V, L90M | L10I, K20I, E35D, M36I, I62V, L63P, I64V, A71V, I72V, I93L |
| >CA20274| codons 1-99 PQITLWQRPIVTIKIGGQLIEALLDTGADDTVLEDINLPGRWKPKIIGGIGGFIKVRQYD QVPVEICGHKVVGTVVVGPTPVNIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |