<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
225.745 BPG225.745 Uganda 1993 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    E35D, M36I, R41K, L63T, H69K, L89M  
>BPG225.745| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QITIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K11Q, V35T, T39A, E40D, K49R, K122E, D123S, I135T, I142V, K173S, D177E, V179I, T200A, Q207A, R211S, V245Q, K281R, L283I, E291ED, I293V, P294T, E312D E29D
>BPG225.745| codons 1-320
PISPIETVPVQLKPGMDGPKVKQWPLTEDKIKALTEICADMEKEGKISRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSQNPEIII
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLIRGTKALTDVVTLTEEAE
LELAENREILKDPVHGVYYD

References
Author Title Citation
Becker-Pergola, G Analysis of HIV type 1 protease and reverse transcriptase in antiretroviral drug naive Ugandan adults. ARHR, 2000