Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| LVMP1270 | LVMP1270 | France | 1999 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, G16E, E35D, M36I, R41K, K45R, L63Q, H69K, L89M |
| >LVMP1270| codons 1-99 PQITLWQRPVVTVKIEGQLKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYD QIQIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K11T, V35T, T39N, E40D, K122E, D123S, A158S, K173T, D177E, T200A, E203D, Q207A, V245Q, L260I, A272P, T286A, E291D, I293V, P294T, E312D, I326V, G335E, M357K, R358G, G359S, E370A, A371V, I375V, T377I, K390R, T403M |
| >LVMP1270| codons 1-421 PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALTEICNDMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRTQNPEIVI YQYMDDLYVGSDLEIGQHRAKIDELRAHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKIVGKLNWASQIYPGIKVKQLCKLLRGAKALTDVVTLTEEAE LELAENREILKDPVHGVYYDPSKDLVAEIQKQGQEQWTYQIYQEPFKNLKTGKYARKGSA HTNDVKQLTAVVQKVAIESIVIWGKTPKFRLPIQKETWEAWWMEYWQATWIPEWEFVNTP P |
References
| Author | Title | Citation |
| Vergne, L | Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: evidence of many minor drug resistance mutations in treatment-naive patients. | J Clin Microbiol, 2000 |