Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| LVMBFE190 | LVMBFE190 | DRC | 1997 | HIV1 | CRF02_AG | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K20I, E35N, M36I, R41K, I64L, H69K, L89M |
| >LVMBFE190| codons 1-99 PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLENINLPGKWKPKMIGGIGGFIKVRQYD QILLEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36D, K49R, V60I, K104R, K122E, D123N, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, V245Q, E248D, S251I, T286A, I293V, P294T, E312D, S322T, G335D, R356K, M357R, R358G, G359S, E370A, A371V, I375V, T377V, K390R, T403M, W406C | K13R |
| >LVMBFE190| codons 1-421 PISPIETVPVKLRPGMDGPKVKQWPLTEEKIKALTDICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEMVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDIWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVTLTEEAE LELAENREILKDPVHGVYYDPTKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRGSA HTNDVKQLTAVVQKVAVESIVIWGKTPKFRLPIQKETWEAWWMEYCQATWIPEWEFVNTP P |
References
| Author | Title | Citation |
| Vergne, L | Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: evidence of many minor drug resistance mutations in treatment-naive patients. | J Clin Microbiol, 2000 |