Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| LVMBS4 | LVMBS4 | DRC | 1997 | HIV1 | CRF02_AG | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, K14R, G16E, K20I, M36I, L63I, H69K, L89M |
| >LVMBS4| codons 1-99 PQITLWQRPIVTVRIEGQLIEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYD QIIIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, K122E, D123G, I142T, A158S, K173I, Q174K, D177E, T200A, Q207E, V245K, A272P, K277R, K281R, E291D, V292I, I293V, D324E, Q334N, G335D, R356K, G359S, T377L, K390R, A400T, E404D |
| >LVMBS4| codons 1-421 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGTRYQYNVLPQGWKGSPSIFQSSMTKILEPFRIKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCRLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKELIAEIQKQGNDQWTYQIYQEPFKNLKTGKYAKMRSA HTNDVKQLTEAVQKIALESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP P |
References
| Author | Title | Citation |
| Vergne, L | Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: evidence of many minor drug resistance mutations in treatment-naive patients. | J Clin Microbiol, 2000 |